BEST: B-cell Epitope prediction using Support vector machine
Tool
This web page provides datasets and prediction model associated with:
Gao J, Faraggi E, Zhou Y, Ruan J, Kurgan L. BEST: improved prediction of B-cell epitopes from antigen sequences. PLoS One. 2012; 7(6):e40104
- Datasets
Each dataset is provided in .txt format.
ChenFrag dataset is available at this link
BCPREDFrag dataset is available at this link
Filtered40_BCPREDFrag
the training dataset with epitopic 20-mers can be downloaded
from here: Filtered40_BCPREDFrag.pos.txt
the training dataset with non-epitopic 20-mers can be downloaded
from here: Filtered40_BCPREDFrag.neg.txt
The SEQ197 test dataset can be downloaded from here: SEQ194.txt
and its source is available at this link
each proteins in this dataset is
represented by UniProt ID, sequence, and annotation of epitopic
residues (using
1) and non-epitopic residues (using 0)
The SEQ19 test dataset can be downloaded from this link
- Prediction model
The model is packaged using ZIP format and can be
downloaded from here:
BEST model ver 1.1.
The ZIP file includes instructions (in README.txt file) how to prepare
and use the predictor.