Replaced putative annotations of secondary structures by PSIPRED with annotations obtained from DSSP using AlphaFold2-predicted protein structures. We continue to provide PSIPRED results for proteins where DSSP fails to assign secondary structure for more than 20% of the residues or if the predicted structure is not available in AlphaFold Database (AlphaFold DB)
Replaced putative annotations of solvent accessibility by ASAquick with annotations obtained from DSSP using AlphaFold2-predicted protein structures. We continue to provide ASAquick results for proteins if it's predicted structure is not available in AlphaFold Database (AlphaFold DB)
Release 2.2 – November 2024
Fixed bugs in creation of individual panels shown in the graphical output
Improved handling of invalid submission
Release 2.1 – July 2024
Significant reduction in data fetching time
Release 2.0 – September 2023
Improved interface to handle entries not found in the database
Replaced putative disorder annotations from older method VSL2B with more accurate and state-of-the-art method flDPnn
Adds putative annotations for 9 types of posttranslational modifications
Redesigns the graphical view by providing new interactive capabilities
Release 1.7 – January 2023
Adds and combines experimental annotations of the secondary structure, intrinsic disorder, and solvent accessibility that are extracted from the PDB and DisProt databases
Release 1.6 – August 2022
Adds annotations for 190 additional genomes
Release 1.5 – February 2022
Provides improved conservation scores by using larger alignment datasets
Release 1.4 – October 2021
Provides new graphical view for a query protein
Release 1.3 – June 2021
Adds normalized solvent accessibility score, residue-level conservation score, and conservation level for each residue of a protein in genome-level downloadable datasets
Provides downloadable protein-level summary for each genome
Release 1.2 – September 2020
Provides search by UniProt entry name
Provides download in json and csv format for a query protein
Provides downloadable graphical view for a query protein
Release 1.1 – June 2020
Includes the statistic summary of database
Provides graphical views for a query protein
Provides search by protein amino acid sequence
Provides download in json format of proteins by genomes
Release 1.0 – May 2020
Includes 13 predicted properties of 1,365,946 proteins from 83 genomes
Includes search by protein UniProt accession entry
Provides download in json format of entire database